Some patients on Crixivan or other protease inhibitor combo therapy are noticing an unusual side effect

April 1998

Some patients on Crixivan or other protease inhibitor combo therapy are noticing an unusual side effect...anaccumulation of fat in the waist, stomach, or the back of the neck.

This syndrome is being called "protease paunch"..."buffalo hump"...or "Crix belly."

It looks like Cushing's syndrome...but it DOESN'T seem to be caused by high cortisol levels like Cushing's.

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Some patients on Crixivan or other protease inhibitor combo therapy are noticing an unusual side effect

Get concise advice on drug therapy, plus unlimited access to CE

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